Whole Genome Amplification
 Emerging technologies are improving the ability to analyze samples with minute amounts of DNA. Large quantities of DNA can be made from miniscule amounts using whole genome amplification methods. DNA from single cells including unicellular organisms, microdissected specimens and forensics samples is easily amplified and suitable for many downstream applications. Several strategies are available for random, unbiased amplification of DNA based on PCR or isothermal amplification methods. Most strategies faithfully amplify the DNA including repeat elements without major drawbacks. Each amplification method has a caveat and hence the method of choice should be tailored to goal of the project. Once amplified, the DNA can be subjected to numerous tests including DNA sequencing, SNP genotyping, fragment (STR) analysis, FISH, microarray analysis, and CHiP. ACGT, Inc. provides several whole genome amplification methods to meet most downstream application needs and consultation services to help you select an appropriate amplification method for your project. |
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